The changes I make on Theme Options Panel can be saved but I'm not able to see them on my live website. (e.g. I changed the header layout in Theme Options and it remained the same on frontend.)
If you're not seeing any errors in your Theme Options and you can save the changes but they're not visible on your website than you might consider the following:
- Make sure you've cleared the cache from both your caching plugin and browser;
- Deactivate all the 3rd party plugins and check if the issue is caused by one you those plugins.
- I make changes and nothing happens on WordPress.org